Sedating antihistamines asthma
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Infrequent adverse effects include urinary retention, palpitations, hypotension, headache, hallucination, and psychosis.-receptors and have a better tolerability profile compared to the first-generation agents.
WINTER/ SPRING/ SUMMER/FALL Limiting Exposure to Allergens in the Home Prevention of Allergy and Asthma in Children Treatment of Allergy and Asthma Skin Testing and Allergy Injection Treatment Inhalers for Asthma Allergic rhinitis and asthma may be effectively treated by a number of medications supplemented by allergen avoidance, and by allergen immunotherapy (allergy injections) when medications and avoidance are inadequate.
The authors of the American College of Chest Physicians Updates on Cough Guidelines (2006) recommend that, for cough associated with the common cold, first-generation antihistamine-decongestants are more effective than newer, non-sedating antihistamines.
First-generation antihistamines include diphenhydramine (Benadryl), carbinoxamine (Clistin), clemastine (Tavist), chlorpheniramine (Chlor-Trimeton), and brompheniramine (Dimetane).
They are effective in the relief of allergic symptoms, but are typically moderately to highly potent muscarinic acetylcholine receptor (anticholinergic) antagonists as well.
These agents also commonly have action at α-adrenergic receptors and/or 5-HT receptors.Histamine, acting on H-antihistamines help against these effects, they work only if taken before contact with the allergen.